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Get Advances in Comparative and Environmental Physiology: PDF

By F. Lang, M. Ritter, H. Völkl, D. Häussinger (auth.), Prof. Dr. Florian Lang, Prof. Dr. Dieter Häussinger (eds.)

One of the necessities for survival is the power of cells to take care of their quantity. therefore, through the process evolution cells have "learned" a number of suggestions to accomplish quantity homeostasis. This quantity regulatory equipment comprises legislation of either, mobile metabolism and mobile shipping and is exploited by means of hormones and transmitters to manage cellularfunction. This e-book to illustrates the complicated interaction of mobile quantity regulatory mechanisms and mobile functionality in a number of tissues. even if, our wisdom continues to be faraway from being conclusive, and the current selection of reports is believed to foster additional experimental efforts to resolve the function of cellphone quantity within the built-in functionality of cells.

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Extra resources for Advances in Comparative and Environmental Physiology: Interaction of Cell Volume and Cell Function

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1991a,c). Remarkably, halfmaximal insulin-induced cell swelling and half-maximal glucagon-induced cell shrinkage in perfused rat liver are found at hormone concentrations normally present in portal venous blood in vivo (vom Dahl et al. 1991c; Fig. 3). Accordingly, one is tempted to speculate that physiological fluctuations of the portal insulin and glucagon concentrations may modify liver cell volume also in vivo. In perfused rat liver, vasopressin exhibits only minor effects on cell volume, but shrinks the cells when added on top of glucagon or cAMP (vom Dahl et al.

1983; Kilberg et al. 1985) and were termed systems A, ASC, Nand L. Systems A and ASC are both Na +-dependent, exhibit overlapping substrate specificities and mediate the electrogenic transport mainly of small aliphatic amino acids, whereas the N a +independent system L accomplishes the electroneutral transport of branched chain and aromatic amino acids. System N is Na+-dependent and electrogenic and is specific for glutamine, histidine and asparagine. System A activity is increased during starvation, feeding of a high protein diet and by hormones such as glucagon and insulin, whereas system N is much less responsive to starvation (Hayes and McGivan 1982).

Am J Physiol 237: ClO-C16 Parker JC (1983a) Hemolytic action of potassium salts on dog red blood cells. Am J Physiol 244: C313-C317 Parker JC (1983b) Volume-responsive sodium movements in dog red blood cells. Am J Physiol 244: C324-C330 Parker JC, Castranova V (1984) Volume-responsive sodium and proton movements in dog red blood cells. J Gen Physiol 84: 379-401 28 F. Lang et al. Parker JC, Gitelman HJ, Glosson PS, Leonard DL (1975) Role of calcium in volume regulation by dog red blood cells. J Gen Physiol 65: 84-96 Pasantes-Morales H, Schousboe A (1988) Volume regulation in astrocytes: a role for taurine as osmoeffector.

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