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Ovarian Cancer in Elderly Patients - download pdf or read online

By Gilles Freyer

This sensible booklet presents up to date details at the specific gains of ovarian melanoma in older ladies and the easiest administration procedure. the total diversity of suitable issues is roofed. tips is equipped on geriatric evaluation, screening, pathology, analysis, and follow-up. a few of the healing procedures are conscientiously defined, overlaying surgical ways, chemotherapy as a first-line method, using anti-angiogenic brokers, and remedy of relapse. The cognitive difficulties that can come up in aged ladies in the course of and after remedy of ovarian melanoma are documented, with recommendation on reaction. tips is usually supplied at the layout of medical trials, and present instructions in organic study are reviewed. This ebook may be of price to either practitioners and researchers with an curiosity in ovarian melanoma and the elderly.​

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Extra resources for Ovarian Cancer in Elderly Patients

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Devouassoux-Shisheboran seen mostly in younger patients. Infiltrative-type mucinous carcinomas have a destructive invasion pattern with desmoplastic stromal reaction and are more likely to have extra-ovarian spread [16, 17]. Mucinous adenocarcinomas may be graded according to their nuclear features [18]. On immunohistochemical study, ovarian mucinous carcinomas show diffuse CK7 positivity, while CK20 is usually less diffusely positive. Hormone receptors (estrogen and progesterone), WT1, and PAX8, are usually negative.

The latter is used to subdivide these mixed tumors into adenosarcomas and carcinosarcomas (malignant mixed mullerian tumor/MMMT) (see also below), respectively. MMMT is a tumor of elderly women seen usually in patients over 60 years old. It is a very high-grade and aggressive neoplasm, often detected at a high stage with extra-ovarian spread and a median survival of less than 24 months [15]. The epithelial component is usually of high-grade serous, endometrioid, and/or clear cell carcinoma. The sarcomatous component may be homologous or heterologous with rhabdomyosarcoma, chondro- or osteo- or liposarcomatous elements.

Prognostic significance of systematic lymphadenectomy as part of primary debulking surgery in patients with advanced ovarian cancer. Gynecol Oncol. 2012;126(3): 381–6. 014. Epub 2012 May 18. 8. Chereau E, et al. Ovarian cancer in the elderly: impact of surgery on morbidity and survival. Eur J Surg Oncol. 2011;37:537–42. 9. Chow WB, et al. Optimal preoperative assessment of the geriatric surgical patient: a best practices guideline from the American College of Surgeon National Surgical Quality Improvement Program and the American Geriatrics Society.

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